I've been trying to understand WSGI and Paste for a while now, and have stayed subscribed to your blog despite not understanding what you were talking about. I kept wondering why you didn't just do something like Rails in Python.
The 0xDECAFBAD blog entry definitely made all the difference for me in understanding what you are doing, and why you are doing it. The 'framework' and 'middleware' words definitely have too much baggage to be used to describe something truly new and innovative. Another way of thinking about it is that we are only starting to see the first web frameworks worthy of the name, and perhaps the same can be said of WSGI as an example of 'real' middleware, at least in the brave new world of web 2.0.
I just wonder whether the Ruby/Rails people will be interested, and if so how they will adopt the ideas. I can't help but think about how cool it would be for the Python and Ruby people to use each others code.
Good work Ian, I hope you see some payback for your perseverance.