That's a good news. I've read the WSGI draft and perceive this as a next major step in maturing of Pythonic web platform. I was also a bit frustrated with WebKit as I feel "this could be done cleaner". While I doubt I could made any significant contribution to your efforts I wish you a good luck!
Personally, for my latest project, I abstracted the portion of WebKit's API I actually use into a facade class to decouple application code as much from WebKit as possible.