Ian Bicking: the old part of his blog

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Here's another idea: "Design and Interpretation of Runtime Systems". Every computer science department on the planet offers a course on compilers, but how many offer a course on the theory and practice of what you have to do at runtime? Linking and loading, byte-code interpreters, just-in-time compilation---there's a lot there, but no-one has ever written it all down in one place.

I think Python would be an running example for such a book, if one included Psyco, IronPython, etc.
Comment on Book Idea: Python Optimization
by Greg Wilson